Volume 8

Number 1 January 2007

Comparison of Granisetron and Granisetron Plus Dexamethasone for the Prevention of Post-operative Nausea and Vomiting (PONV)

DOI: https://doi.org/10.47648/jmsr.2007.v0801.04

Islam K S1 , Bakhtiar S M2 , Mannan M A3

Abstract

77tere is a high incidence of postoperative nausea and vomiting (PONV) in patients undergoing surer, and anaesthesia. Many factors are claimed to be responsible for POW. This stad.v MU designed to compare the effectiveness of grornsetron pits desomethasone with gran isetron alone to prevent post-operative nausea and vomiting. In this randomised double blind study. sixty patients were divided into two egnal groups ( n=30 each ). Patients in Group A received granisetron 40 pion per kg before inductor of anaesthesia and those in Group B received gmnisetron 40 pp: per kg phis devamethasone 8 nog before induction of anaesthesia. All the patients were observed for post-opera tive nausea and vaniting for 24 hours (0-6 hours in the recovety room and 18 hours in ward or cabin). A significant difference was found in complete response, defined as no pos,opertalve nausea and vomiting. between patients of graniserron alone group and those of granisetron pins dexamethasone combination group. The combination of grontsoron plus de.tainethasone is considered to be more effective for prevention of post-operative nausea and vomiting.

Keywords:


  1. Resident, Department of Anacsthesiology

    Holy Family Red Crescent Medical College, Dhaka

  2. Consultant, Department of Anacsthesiology

    Holy Family Red Crescent Medical College, Dhaka

  3. Associate Professor and Head of the department of Anaesthesiology

    Holy Family Red Crescent Medical College, Dhaka

Download PDF File Cite

Volume 8, Number 1 January 2007
Page: 21-27