Volume 17
Number 2 July 2011Hasan ASM Q1 , Ahmed A2 , Daulatuzzaman Md.3
Abstract
Langerhans cell histiocytosis is a term that encompasses a spectrum of clinical conditions ranging from a single, sometimes self limited osteolytic bone lesion to a fulminant. disseminated process that may be fatal. Three clinical subtypes of Langerhans cell histiocytosis are Hand-Schuller-Christian disease, Letterer-Siwe disease and eosinophilic granuloma. Farber recognized a histological similarity among these disparate conditions. and Lichtenstein suggested that although certain differences existed between groups of patients, a reliable distinction could not he made in individual cases on the basis of histopathology alone.' Lichtenstein introduced the term histiocytosis X to denote a proliferation of histioeytes, with "X" to convey the uncertain histogenesis of the disease.
Keywords:
- Associate Professor of Neurosurgery
- Lecturer, Department of Pathology
- Associate Professor. Department of ENT