Volume 27

Number 2 July 2017

Antibiotics in ICU : The Challenges of Use, Cost and Response in a Tertiary Care Hospital

DOI: https://doi.org/10.47648/jmsr.2017.v2702.06

Perveen R A1 , Nasir M2 , Farha N3 , Islam M A 4

Abstract

"

Antibiotic resistance can lead to increased morbidity, mortality, length of hospital stay, and health care expenditures. The study is designed to observe the challenges of antibiotic consumption, related costs and their resistance pattern in critically ill patients. The study was conducted in ICU from July to December 2016, in Holy Family Red Crescent Medical College Hospital The demographic data, antibiotic sensitivity report, the administration ofdifferent classes of antibiotics as well as individual drugs and their costs were recorded. In 216 patients, meropenem was the most commonly prescribed antibiotic followed by levofloxacin and ceftriaxone. Meropenem with one or more class of antibiotics had the higher cost (1985/-and 2800/- BDT/ per day) per patient. Though the cephalosporins are the initial choice as the safest, cheaper antibiotics in developed countries, but high rate of resistance was observed in this ICU. The overall sterilization and strict control of nosocomial infections may play vital role in overcoming the challenges. Use of local antibiogram, narrow spectrum antibiotics, infectious disease specialist consultation, and restricted authorization to prescribe antibiotics can effectively shift the antibiotic sensitivity and minimize the cost in ICU stay.

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Keywords:


  1. Assistant Professor, Department of Pharmacology

    Holy Family Red Crescent Medical College, Dhaka

  2. Professor and Head, Department of Pharmacology

    Holy Family Red Crescent Medical College, Dhaka

  3. Assistant Professor, Department of Pharmacology

    Holy Family Red Crescent Medical College, Dhaka

  4. Assistant Professor, Department of Otolaryngology

    International Medical College, Dhaka

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Volume 27, Number 2 July 2017
Page: 31-37