Hyperemesis graviderum is a complication of pregnancy that can lead to severe maternal nutritional deprivation. About 0.14% -1.3% of pregnant women sufferedfrom hyperemesis graviderum. Women with hyperemesis grmidanan causing loss of greater than 5% of their pre-pregnancy weight. And has been linked to fetal growth restriction, wernickes encephalopathy resulting in fetal death in 40% of cases . Ilyperemesis graviderzaninterfire there working life, it is important to know the outcome of hyperemesis graviderum on fetus and mother. A tertiary level hospital based prospective study was conducted on woman suffering from Hyperemesis graviderum and attended in OPD and 1F'D of Holy Family Red Crescent Medical College Hospital, Bangladesh to asses the adverse outcome of Hyperemesis Graviderum on .mother and baby and identifies its determinants. The mean age of the study group was 26.2513.25 years. Regarding parity, 54.0% patients were found primipara and 46.0% patients found multipara. The majority of the subjects (66%) were normal weight, 18% patients had overweight by BM1 (body mass index) 12% patients were underweight and 4% patients were obese. Distribution of the study subjects according to educational status, it was found that 32% were primary, 44% patients were high school, 12% patients were SSC, 8% patients were HSC and 4% patients were graduate and above. Out of 50 cases, 64% were housewife, 18% patients were service, 4% patients were business and 10% patients were student. Majority of patients (70%) had positive family history of hyperemsisgravidenn. Study showed 46% respondent started vomiting within 6-10 gestational weeks, 30% started vomiting more than 10 gestational weeks and 24% started vomiting within 1-5 gestational weeks. Maximum subjects (78%) needed home treatment and 22% patients were hospitalization. Most of the patients (68.0%) hemoglobin level 6- 10mg/d 1 . Maximum were rhesus positive blood group. Most of the patients 98% had normal serum creatinine level, 86% patients had normal serum electrolytes, 94% patients had normal urine R/M/E, 78% patients had normal RS'S level, 100% patients of hyperemesis gravidunn patients ultrasonography reports in pregnancy was normal. Among 50 patients, 4% patients had abortion history, 2% cases had IUD, 44% patients had IUGR and 10% patients had AGA in pre-term pregnancy. Out of 23 term pregnancy, 24% cases had 1UGR and 22% cases had AGA. Two percent neonatal death after delivery. hyperemesis Graviderum is related to maternal age, parity, education level, body mass index, occupation of the patients, education level, family history of hyperemesis graviderum and adverse outcome on mother and baby.