Volume 20

Number 1 January 2013

Clinico-demographic Characteristics of Patients with Cirrhosis of Liver : Experienced at a Tertiary Care Hospital

DOI: https://doi.org/10.47648/jmsr.2013.v2001.02

Kabir AKM S1 , Alam Md. F2 , Ghosh C K3 , Ahmed S N4 , Sikder S5

Abstract

Cirrhosis of liver is one of the commonest hepatobiliary problems in Bangladesh as well as in global perspective. The purpose of the present study was to find out the clinico-demographic characteristics of liver cirrhosis patients admitted at a tertiary care hospital. Patients who are clinically suspected to have cirrhosis of liver, admitted in medicine units of Holy Family Red Crescent Medical College Hospital, Dhaka have been analyzed regarding clinical presentation and complications profile. Total 100 patients were included of which 84% were cirrhosis of liver, 7% were chronic active hepatitis, 3% were chronic persistent hepatitis, 2% were Wilson's disease with cirrhosis and 4% were hepatocellular carcinoma (HCC) on the top of cirrhosis of liver. The peak age incidence was between 31-50 years with male-female ratio of 4.88:1. History of jaundice (42%), parenteral medications (14%), infusion (6%) and abdominal surgery (4.0%) were important findings from patient's past history. History of alcohol intake was found in only 4% cases. Overall, weakness (78%), anorexia (72%), abdominal swelling (74%), weight loss (64%), ankle swelling (42%), low grade fever (35%) and yellowish discolouration of eyes, skin and urine (37%) were the most common symptoms. Common signs, revealed by clinical examination as a whole, were anaemia (55%), ascites (68%), oedema (52%), jaundice (34%), palpable spleen (55%) and hepatic facies (37%). Cirrhosis of liver most commonly occurs in middle aged male patients. Weakness, weight loss, anorexia, abdominal discomfort/dyspepsia and swelling of the abdomen are the most prevalent symptoms.

Keywords:


  1. Associate Professor, Dept. of Medicine

    Holy Family Red Crescent Medical College, Dhaka

  2. Associate Professor, Dept. of Medicine

    Holy Family Red Crescent Medical College, Dhaka

  3. Assistant Professor, Dept. of Gastroenterology

    Bangabandhu Sheikh Mujib Medical University

  4. Assistant Professor, Dept. of Medicine

    Holy Family Red Crescent Medical College, Dhaka

  5. Assistant Professor, Dept of Nephrology

    Holy Family Red Crescent Medical College, Dhaka

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Volume 20, Number 1 January 2013
Page: 45152