Acute myocardial infarction (AMI) can occur in young people but still relatively rare in young women. AMI is the interruption of blood supply to the heart, causing heart cells to die commonly due to occlusion of a coronary artery following the rupture of a vulnerable atherosclerotic plaque which is an unstable collection of lipid (fatty acids) and white blood cells (especially macrophages) in the wall of an artery. The resulting ischemia (restriction in blood supply) and oxygen if left untreated for a sufficient period of time can cause damage or death (infarction of heart muscle tissue myocardiam). The contributory risk factors for atherosclerosis and ischcmic heart diseases (II-ID) arc generally common for ML These arc diabetes, smoking, low HDL. high Triglycerides (TG). Low level of High density lipoprotein cholesterol (HDL -C) is a predictable risk factor in the development of atherosclerosis and IHD in women than in men. Low HDL is one of the most common lipid disorders in patient with premature coronary heart disease. Current European and US guideline showed elevated TG and low HDL levels are common lipid abnormalities even in the absence of raised LDL-C although guideline identifies the reduction of LDL level as the primary for the treatment of dyslipidaemia'. Framingham heart study population showed that reduction of I mg / dl of FIDL leads to an increase in risk by about 2-3 % of coronary heart disease in both scx2. This case highlighted the possibility of the development of AMI in young female patient with dyslipideinia (Low HDL and high TG).